发明名称 FUCOSYLATION-DEFICIENT CELLS
摘要 A cell as provided that expresses a GDP-4-keto-6-deoxy-mannose-3,5-epimerase-4-reductase (FX) protein with a modification, wherein the cell lacks or substantially lacks the ability to fucosylate a glycoprotein at a first temperature, but does not lack or does not substantially lack the ability to fucosylate the glycoprotein at a second temperature. Methods for making antigen binding proteins are also provided which use the cell.
申请公布号 IL216624(D0) 申请公布日期 2012.02.29
申请号 IL20110216624 申请日期 2011.11.27
申请人 REGENERON PHARMACEUTICALS, INC. 发明人
分类号 C12N 主分类号 C12N
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