发明名称 |
LIQUID COMPOSITION OF FACTOR VII POLYPEPTIDES |
摘要 |
The invention concerns a liquid aqueous composition comprising (i) a factor VII polypeptide, (ii) an agent suitable for keeping pH in the range of from about 4.0 to about 9.0; (iii) an agent selected from the group consisting of: a calcium salt, a magnesium salt, or a mixture thereof; wherein the concentration of (iii) is less than 15 mM; and (iv) An ionic strength modifying agent; wherein the ionic strength of the composition is at least 200 mM. |
申请公布号 |
EP1641487(B1) |
申请公布日期 |
2012.02.29 |
申请号 |
EP20040738944 |
申请日期 |
2004.06.24 |
申请人 |
NOVO NORDISK HEALTH CARE AG |
发明人 |
HANSEN, BIRTHE, LYKKEGAARD;JENSEN, MICHAEL, BECH;KORNFELT, TROELS |
分类号 |
A61K9/00;A61K31/19;A61K38/48;A61K47/02;A61K47/18;A61K47/26 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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