发明名称 |
LOCAL THERAPEUTIC RELEASE DEVICE |
摘要 |
<p>An oral delivery device for the treatment of periodontal disease, the device being in a solid unit dosage form configured for insertion into a periodontal pocket of a patient. The device consists of: (a) a biodegradable pharmaceutically acceptable water-insoluble polymer in the form of a matrix; (b) a therapeutically effective amount of at least one anti-inflammatory agent dispersed within the matrix; (c) optionally a plasticizing agent; (d) optionally at least one of a wetting agent, a suspending agent and a dispersing agent; and (e) optionally an enzymatically biodegradable pharmaceutically acceptable water soluble polymer dispersed within the matrix. The biodegradable water-insoluble polymer is degradable by enzymatic degradation, physical disintegration or a combination thereof. Also disclosed is a periodontal implant comprising the device and a method for the treatment of periodontal disease comprising administering to a periodontal pocket of a patient in need of such treatment the delivery device.</p> |
申请公布号 |
SG177354(A1) |
申请公布日期 |
2012.02.28 |
申请号 |
SG20110096120 |
申请日期 |
2010.06.24 |
申请人 |
DEXCEL PHARMA TECHNOLOGIES LTD. |
发明人 |
PENHASI, ADEL;REUVENI, ALBERT;SHOSHANI, EYAL |
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