发明名称 Naphthylacetic acids
摘要 The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein X, Q, and R1-R6 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists or partial agonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.
申请公布号 US8124629(B2) 申请公布日期 2012.02.28
申请号 US20090614478 申请日期 2009.11.09
申请人 FIROOZNIA FARIBORZ;GILLESPIE PAUL;LIN TAI-AN;MERTZ ERIC;SIDDURI ACHYUTHARAO;SO SUNG-SAU;TAN JENNY;THAKKAR KSHITIJ CHHABILBHAI;HOFFMANN-LA ROCHE INC. 发明人 FIROOZNIA FARIBORZ;GILLESPIE PAUL;LIN TAI-AN;MERTZ ERIC;SIDDURI ACHYUTHARAO;SO SUNG-SAU;TAN JENNY;THAKKAR KSHITIJ CHHABILBHAI
分类号 A61K31/44;A61K31/192;C07C63/64;C07D211/54 主分类号 A61K31/44
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