发明名称 |
Naphthylacetic acids |
摘要 |
The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein X, Q, and R1-R6 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists or partial agonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma. |
申请公布号 |
US8124629(B2) |
申请公布日期 |
2012.02.28 |
申请号 |
US20090614478 |
申请日期 |
2009.11.09 |
申请人 |
FIROOZNIA FARIBORZ;GILLESPIE PAUL;LIN TAI-AN;MERTZ ERIC;SIDDURI ACHYUTHARAO;SO SUNG-SAU;TAN JENNY;THAKKAR KSHITIJ CHHABILBHAI;HOFFMANN-LA ROCHE INC. |
发明人 |
FIROOZNIA FARIBORZ;GILLESPIE PAUL;LIN TAI-AN;MERTZ ERIC;SIDDURI ACHYUTHARAO;SO SUNG-SAU;TAN JENNY;THAKKAR KSHITIJ CHHABILBHAI |
分类号 |
A61K31/44;A61K31/192;C07C63/64;C07D211/54 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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