发明名称 2-AMINO-7,8-DIHYDRO-6H-PYRIDO(4,3-d)PYRIMIDIN-5-ONES, PROCESS FOR THEIR PREPARATION, METHOD OF THERAPY USING THEREOF, A COMPONENT COMPOSITION, A COMPOSITION AND MEDICAMENT BASED THEREON, 2-4-DIOXOPIPERIDINE COMPOUNDS FOR THEIR PRODUCTION
摘要 Disclosed are 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, their stereoisomers, tautomers and pharmaceutically acceptable salts, compositions that include a pharmaceutically acceptable carrier and one or more of the 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, either alone or in combination with at least one additional therapeutic agent. Disclosed also are methods of using the 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of viral, autoimmune, cardiovascular, and central nervous system diseases and diseases associated with cellular proliferative.
申请公布号 EA016152(B1) 申请公布日期 2012.02.28
申请号 EA20080000992 申请日期 2006.09.28
申请人 NOVARTIS AG 发明人 MACHAJEWSKI TIMOTHY, D.;SHAFER CYNTHIA, M.;MCBRIDE CHRISTOPHER;ANTINIOS-MCCREA WILLIAM;DOUGHAN BRANDON, M.;LEVINE BARRY, H.;XIA YI;MCKENNA MAUREEN;WANG X. MICHAEL;MENDENGALL KRIS;ZHOU YASHEEN;GONG BAOQING;GU DAN;DOLAN JOHN;TULINSKY JOHN;BRINNER KRISTIN;GAO ZHENHAI;BARSANTI PAUL, A.;BRAMMEIER NATHAN;COSTALES ABRAN;LIN XIAODONG;PICK TERESA;POON DANIEL;RENHOWE PAUL, A.;ROCO ALICE
分类号 C07D471/04;A61K31/519;A61P35/00;C07D211/86 主分类号 C07D471/04
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