发明名称 SOLID DRUG TABLETS FOR IMPLANTABLE DRUG DELIVERY DEVICES.
摘要 A drug dosage form is provided in the form of a solid tablet which is greater than 50% by weight the local anesthetic agent. The local anesthetic agent may be selected from the group consisting of an aminoamide, an aminoester, and a combination thereof. The drug tablet may be in the form of a mini-tablet which is greater than 70 wt% drug, with the balance being excipient. For example, the anesethetic agent may include lidocaine, in a salt or base form, combined with binder and lubricant excipients. Implantable drug delivery devices including the tablets are also provided, e.g., one or more of the drug tablets may be contained in a biocompatible housing. The drug tablets may be substantially cylindrical with flat end faces, and the device may have from 10 to 100 drug tablets aligned in the housing with the flat end faces of adjacent tablets abutting one another.
申请公布号 MX2011013539(A) 申请公布日期 2012.02.28
申请号 MX20110013539 申请日期 2010.06.28
申请人 TARIS BIOMEDICAL, INC. 发明人 HEEJIN LEE;CHERYL LARRIVEE-ELKINS;KAREN DANIELLE DANIEL;BURLEIGH M. HUTCHINS III
分类号 A61M31/00;A61K9/00;A61K9/20;A61K31/167 主分类号 A61M31/00
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