发明名称 |
METHOD FOR DETERMINATION OF ONSET RISK OF GLAUCOMA |
摘要 |
<p>METHOD FOR DETERMINATION OF ONSET RISK OF GLAUCOMAA method of determining the presence or the absence of a glaucoma risk, including the steps of detecting in vitro an allele and/or a genotype of asingle nucleotide polymorphism which is located on a 31st base of a base sequence, in a sample from a subject, wherein the base sequence is at least one base sequence selected from the group consisting of base sequences shown in SEQ ID NOs: 203 to 514 or a complementary sequence thereto (step A), and comparing the allele and/or the genotype detected in the stepA with at least one of an allele and/or a genotype, containing a high-risk allele, in the base sequences shown in SEQ ID NOs: 203 to 514 (step B). According to the method of the present invention, the level of an onset risk of glaucoma in a sample donor can be determined by analyzing an allele or a genotype of a single nucleotide polymorphism in the present invention onthe sample, so that the sample donor can take a preventive measure of glaucoma, or can receive appropriate treatments, on the basis of this risk.No Figure</p> |
申请公布号 |
SG177960(A1) |
申请公布日期 |
2012.02.28 |
申请号 |
SG20120001400 |
申请日期 |
2008.04.17 |
申请人 |
SANTEN PHARMACEUTICAL CO., LTD.;KINOSHITA, SHIGERU;TASHIRO, KEI |
发明人 |
KINOSHITA, SHIGERU;TASHIRO, KEI;NAKANO, MASAKAZU;YAGI, TOMOHITO;MORI, KAZUHIKO;IKEDA, YOKO;TANIGUCHI, TAKAZUMI;KAGEYAMA, MASAAKI |
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