发明名称 |
LUTEINIZING HORMONE LIQUID FORMULATIONS |
摘要 |
Disclosed is a liquid formulation containing luteinizing hormone (LH) or a variant thereof characterized in that said formulation comprises a phosphate buffer and a stabilizing amount of arginine or salts thereof at a concentration of at or about 10 to at or about 50 mg/ml and/or lysine or salts thereof at a concentration of at or about 10 to at or about 50 mg/ml. Use of the formulation in a medicament for treatment of infertility and the use in combination with follicle-stimulating hormone (FSH) is also disclosed.
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申请公布号 |
NZ583991(A) |
申请公布日期 |
2012.02.24 |
申请号 |
NZ20080583991 |
申请日期 |
2008.10.29 |
申请人 |
MERCK SERONO S.A |
发明人 |
AGOSTINETTO, RITA;SAMARITANI, FABRIZIO;DEL RIO, ALESSANDRA;RICHARD, JOEL |
分类号 |
A61K9/08;A61K38/24;A61P5/06 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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