发明名称 NOVEL 2-AMINOOXAZOLINES AS TAAR1 LIGANDS FOR CNS DISORDERS
摘要 Disclosed herein are the use of 2-amniooxazolines of formula I, wherein the substituents are as defined with in the specification, in the manufacture of medicaments for the treatment of diseases related to the biological function of the trace amine associated receptors, which diseases are anxiety disorders, bipolar disorder, psychotic disorders, neurological diseases, Parkinson's disease, neurodegenerative disorders, Alzheimer's disease, epilepsy, migraine and metabolic disorders, diabetes, diabetic complications, dyslipidemia, disorders of energy consumption and assimilation and disorders and malfunction of body temperature homeostasis. Also disclosed are compounds of formula (I-A)-(I-H), processes for their preparation and medicaments comprising said compounds.
申请公布号 NZ578260(A) 申请公布日期 2012.02.24
申请号 NZ20080578260 申请日期 2008.01.23
申请人 F. HOFFMANN-LA ROCHE AG 发明人 GALLEY, GUIDO;GROEBKE ZBINDEN, KATRIN;NORCROSS, ROGER;STALDER, HENRI
分类号 A61P3/04;A61K31/421;A61P25/00;C07D263/28;C07D413/04 主分类号 A61P3/04
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