Molecular diagnosis and classification of malignant melanoma using RGS1, ARPC2, FN1, SPP1 and WNT-2 polypeptide markers

摘要

Disclosed is a method of diagnosing melanoma in a subject, the method comprising the steps of: a) contacting a biological sample from the subject with five reagents, each one of which specifically binds to a marker consisting of (i) the polypeptides RGS1, ARPC2, FN 1, SPP1 and WNT-2 or (ii) the nucleic acids encoding the polypeptides; and b) determining whether or not each of the selected markers is over expressed in the sample; thereby providing a diagnosis for melanoma in the subject.