发明名称 IMIDAZOQUINOLINES WITH IMMUNO-MODULATING PROPERTIES
摘要 Disclosed are imidazoquinolines represented by general formula (I), such as methyl 2-(4-((3-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)propylamino)methyl)phenyl)acetate, or pharmaceutically acceptable salts thereof. Also discloses is the use of the compounds of formula (I) for treating allergic or viral diseases or cancers or for use in treating asthma, COPD, allergic rhinitis, allergic conjunctivitis, atopic dennatitis, cancer, hepatitis B, hepatitis C, HIV, HPV, bacterial infections and dennatosis, as well as diseases in which modulation of TLR7 activity is beneficial.
申请公布号 NZ580622(A) 申请公布日期 2012.02.24
申请号 NZ20080580622 申请日期 2008.05.06
申请人 DAINIPPON SUMITOMO PHARMA CO. LTD.;ASTRAZENECA AB 发明人 BONNERT, ROGER VICTOR;MCINALLY, THOMAS;THOM, STEPHEN;WADA, HIROKI
分类号 C07D471/04;A61K31/437;A61P37/02 主分类号 C07D471/04
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