Artificial kidney precursor comprising a non-human mammalian metanephros and process for the production thereof

摘要

Disclosed is an artificial kidney precursor comprising a non-human mammalian metanephros separated out from a living body, wherein the metanephros has been subjected to freezing and thawing treatments outside a living body, and comprises mammalian mesenchymal stem cells transferred outside a living body. Further disclosed is a method of producing an artificial kidney precursor, comprising the steps of: (I) freezing a mammalian metanephros separated out from a living body; (II) thawing the frozen mammalian metanephros; and (III) transferring mammalian mesenchymal stem cells into the metanephros outside a living body before the freezing (I) or after the thawing (II).