发明名称 HUMAN BINDING MOLECULES CAPABLE OF NEUTRALIZING INFLUENZA VIRUS H5N1 AND USES THEREOF
摘要 An isolated human binding molecule capable of recognizing and binding to an epitope in the HA2 subunit of the influenza haemagglutinin protein (HA), characterized in that said binding molecule has neutralizing activity against an influenza virus comprising HA of the H5 subtype, such as H5N1, H5N2, H5N8, and H5N9, and in that said binding molecule comprises the VH germline VH1-69.
申请公布号 NZ574581(A) 申请公布日期 2012.02.24
申请号 NZ20070574581 申请日期 2007.09.06
申请人 CRUCELL HOLLAND B.V. 发明人 VAN DEN BRINK, EDWARD, NORBERT;DE KRUIF, CORNELIS ADRIAAN;THROSBY, MARK
分类号 C07K16/10;A61K39/145;C12N5/10;C12N15/09 主分类号 C07K16/10
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