发明名称 TOPICAL STABILIZED PROSTAGLANDIN E COMPOUND DOSAGE FORM
摘要 <P>PROBLEM TO BE SOLVED: To provide non-aqueous prostaglandin E compound dosage forms suitable for the treatment of sexual dysfunction or the like, in male as well as female patients. <P>SOLUTION: In the packaged prostaglandin E dosage form containing a sealed actives compartment and a sealed inerts compartment, the sealed actives compartment contains: 0.025 to 10 pts.wt. of a prostaglandin E<SB POS="POST">1</SB>; 0.025 to 10 parts pts.wt. of dodecyl 2-(N,N-dimethylamino)-propionate or a salt thereof; and 1-50 pts.wt. of lactose. Also, the sealed inerts compartment contains: 0.05 to 2.5 pts.wt. of hydroxypropyl methyl cellulose; 0.001 to 5 pts.wt. of silicone antifoam agent; 0.5-25 pts.wt. of hydroxypropyl-&beta;-cyclodextrin, 5-75 pts.wt. of ethanol, and 5-75 pts.wt. of water. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012036196(A) 申请公布日期 2012.02.23
申请号 JP20110200752 申请日期 2011.09.14
申请人 NEXMED HOLDINGS INC 发明人
分类号 A61K31/5575;A61K9/00;A61K9/06;A61K9/70;A61K31/557;A61K47/10;A61K47/14;A61K47/18;A61K47/24;A61K47/26;A61K47/36;A61K47/38;A61K47/40;A61P1/04;A61P3/00;A61P9/00;A61P15/10;A61P17/02 主分类号 A61K31/5575
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