发明名称 ANTIBODIES TO EGFL7 AND METHODS FOR THEIR USE
摘要 <P>PROBLEM TO BE SOLVED: To provide compositions and methods that are useful for modulating vascular development. <P>SOLUTION: The present invention relates to antibodies that bind to the Epidermal Growth Factor-Like Domain 7 (EGFL7). The antibodies are produced by expressing vectors containing polynucleotides in a host cell, wherein the polynucleotides code the antibodies. The administration of the antibodies or a composition containing the antibodies, preferably the further administration of anti-angiogenic agent, enables angiogenesis in a subject having a pathological condition associated with angiogenesis to be reduced or inhibited. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012036205(A) 申请公布日期 2012.02.23
申请号 JP20110213087 申请日期 2011.09.28
申请人 GENENTECH INC 发明人 YE WEILAN;SCHMIDT MAIKE;HONGO JO-ANNE;WU YAN
分类号 C07K16/22;A61K39/395;A61P9/00;A61P27/02;A61P35/00;A61P37/06;C12N15/09;C12P21/08 主分类号 C07K16/22
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