发明名称 |
C6ORF167 AS A TARGET GENE FOR CANCER THERAPY AND DIAGNOSIS |
摘要 |
Objective methods for diagnosing cancer or a predisposition to developing cancer, particularly lung cancer are described herein. The present invention provides a diagnostic method that utilizes the expression level of C6orf167 as an index of cancer. The present invention further provides methods of screening for therapeutic substances useful in the treatment of cancer, e.g. lung cancer. The invention further provides methods of inhibiting the cancer cell growth and either or both of treating and preventing cancer. The invention also features double stranded molecules against C6orf167 gene and an inhibitory polypeptide for NFKBIL2, as well as vector encoding them and compositions containing them. |
申请公布号 |
WO2012023259(A1) |
申请公布日期 |
2012.02.23 |
申请号 |
WO2011JP04507 |
申请日期 |
2011.08.09 |
申请人 |
ONCOTHERAPY SCIENCE, INC.;DAIGO, YATARO;NAKAMURA, YUSUKE;TSUNODA, TAKUYA |
发明人 |
DAIGO, YATARO;NAKAMURA, YUSUKE;TSUNODA, TAKUYA |
分类号 |
C12N15/09;A61K48/00;C07K14/47;C12N15/113;C12Q1/68;G01N33/574 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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