| 发明名称 |
GLYCOSAMINOGLYCAN-ANTAGONISING MCP-I MUTANTS AND METHODS OF USING SAME |
| 摘要 |
Novel mutants of human monocyte chemoattractant protein 1 (MCP-1) with increased glycosaminoglycan (GAG) binding affinity and knocked-out or reduced GPCR activity compared to wild type MCP-1, and their use for therapeutic treatment of inflammatory diseases.
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| 申请公布号 |
US2012046218(A1) |
申请公布日期 |
2012.02.23 |
| 申请号 |
US201013145217 |
申请日期 |
2010.01.29 |
| 申请人 |
KUNGL ANDREAS;PROTAFFIN BIOTECHNOLOGIE AG |
发明人 |
KUNGL ANDREAS |
| 分类号 |
A61K38/19;A61K31/711;A61P1/00;A61P9/04;A61P9/10;A61P25/00;A61P27/02;A61P29/00;A61P37/00;C07K14/52;C12N1/21;C12N15/19;C12N15/70 |
主分类号 |
A61K38/19 |
| 代理机构 |
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代理人 |
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