发明名称 |
METHOD FOR INHIBITING THE INDUCTION AND FORMATION OF OSTEOCLASTS |
摘要 |
Methods for (i) inhibiting the induction and formation of osteoclasts, (ii) inhibiting RANKL expression in osteoblasts, (ii) inhibiting the activation of osteoclasts and (iv) inhibiting a decrease in bone density by administering to a warm-blooded animal in need thereof a pharmacologically effective amount of a compound selected from the group consisting of olmesartan and olmesartan medoxomil, a pharmacologically acceptable salt thereof or a pharmacologically acceptable ester thereof.
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申请公布号 |
US2012046327(A1) |
申请公布日期 |
2012.02.23 |
申请号 |
US201113235768 |
申请日期 |
2011.09.19 |
申请人 |
MORISHITA RYUUICHI;NAKAGAMI HIRONORI;SHIMIZU HIDEO;OSAKA UNIVERSITY;DAIICHI SANKYO COMPANY, LIMITED |
发明人 |
MORISHITA RYUUICHI;NAKAGAMI HIRONORI;SHIMIZU HIDEO |
分类号 |
A61K31/4178;A61P19/08 |
主分类号 |
A61K31/4178 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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