| 发明名称 |
TREATMENT OF TRISTETRAPROLINE (TTP) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO TTP |
| 摘要 |
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Tristetraproline (TTP), in particular, by targeting natural antisense polynucleotides of Tristetraproline (TTP). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of TTP. |
| 申请公布号 |
US2012046236(A1) |
申请公布日期 |
2012.02.23 |
| 申请号 |
US201013318700 |
申请日期 |
2010.05.06 |
| 申请人 |
COLLARD JOSEPH;KHORKOVA SHERMAN OLGA;OPKO CURNA LLC |
发明人 |
COLLARD JOSEPH;KHORKOVA SHERMAN OLGA |
| 分类号 |
A61K31/7088;A61K31/7115;A61K31/712;A61K31/7125;A61K31/713;A61K38/14;A61P1/00;A61P3/00;A61P3/04;A61P9/00;A61P9/04;A61P9/10;A61P19/02;A61P29/00;A61P35/00;C07H21/00;C07K2/00;C12N5/071;C12Q1/68;G01N21/64;G01N25/04 |
主分类号 |
A61K31/7088 |
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