| 摘要 |
7-(Azacycloalkyl-methyl)-benzothiophene or benzofuran derivatives of formula (I), in the form of enantiomers, diastereomers and mixtures (including racemic mixtures), and their salts are new. A = H or OH; X = S or O; R1, R2, R4 = H, halo, CN, alkyl, 2-6C alkenyl, 3-6C cycloalkyl, 3-6C cycloalkenyl, 6-14C aryl, alkoxycarbonyl, hydroxyalkyl, alkoxy, alkoxyalkyl, fluoroalkyl or 1-2C perfluoroalkyl; or R1 + R2 = 1-6C alkylene, 3-6C alkenylene or fused phenyl ring; R3 = H, alkyl, 2-6C alkenyl, fluoroalkyl, 1-2C perfluoroalkyl, 3-6C cycloalkyl, 3-6C cycloalkenyl, phenyl, benzyl or alkoxycarbonyl; R5 = H or halogen; a , c = 0 or 1; b = 0, 1 or 2; n = 1-6; alkyl moieties have 1-6C unless specified otherwise.
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