Targeted binding agents directed to PDGFR-alpha and uses thereof
摘要
Targeted binding agents directed to the antigen PDGFR-alpha and uses of such agents are disclosed herein. More specifically the invention relates to fully human monoclonal antibodies directed to the antigen PDGFR-alpha and uses of these antibodies. Aspects of the invention also relate to hybridomas or other cell lines expressing such antibodies. The described targeted binding agents and antibodies are useful as diagnostics and for the treatment of diseases associated with the activity and/or overexpression of PDGFR-alpha.
申请公布号
EP2420514(A1)
申请公布日期
2012.02.22
申请号
EP20110171222
申请日期
2007.08.02
申请人
MEDIMMUNE LIMITED
发明人
BLAKEY, DAVID CHARLES;CARTLIDGE, SUSAN ANN;FOLTZ, IAN;GAZIT-BORNSTEIN, GADI;KANG, JASPAL SINGH;LAING, NAOMI;TAYLOR, LAURA;YANG, XIAODONG