发明名称 |
Enhanced bioavailability of octreotide vis the GI tract using a suspension in a hydrophobic medium |
摘要 |
The pharmaceutical compositions described herein include a suspension which comprises an admixture in solid form of a therapeutically effective amount of a therapeutic agent and at least one salt of a medium chain fatty acid and a hydrophobic medium, e.g. castor oil or glyceryl tricaprylate or a mixture thereof. The pharmaceutical compositions described herein contain medium chain fatty acid salts and are substantially free of alcohols. The pharmaceutical compositions may be encapsulated in a capsule. Methods of treating or preventing diseases by administering such compositions to affected subjects are also disclosed. |
申请公布号 |
GB2463978(B) |
申请公布日期 |
2012.02.22 |
申请号 |
GB20090016349 |
申请日期 |
2009.09.17 |
申请人 |
CHIASMA INC |
发明人 |
PAUL SALAMA;RONI MAMLUK;KAREN MAROM;IRINA WEINSTEIN;MOSHE TZABARI |
分类号 |
A61K9/10;A61K38/11;A61K38/14;A61K38/16;A61K38/21;A61K38/26;A61K38/31;A61K47/12;A61K47/14;A61P3/00;A61P3/04;A61P31/00;A61P35/00;A61P37/00 |
主分类号 |
A61K9/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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