发明名称 THEANINE DERIVATIVES, PREPARATION METHOD THEREOF AND COMPOSITION OF THE SKIN EXTERNAL APPLICATION FOR ANTI-ACNE CONTAINING THE SAME
摘要 PURPOSE: A theanine derivative and an external use skin composition containing the same are provided to ensure selective antibacterial effect against propionibacterium acne. CONSTITUTION: A theanine derivative is denoted by chemical formula 1 or 2. In chemical formulas 1 and 2, R1 and R2 are hydrogen, methyl, ethyl, propyl, isopropyl, n-butyl, isobutyl, or t-butyl. An external use skin composition for anti-acne contains 0.001-20.0 wt% of the theanine derivative as an active ingredient. A method for preparing the theanine derivative of chemical formula 1 or 2 comprises: a step of heating compound A and maltose in a reaction solvent and stirring; and a step of depositing a product after reaction. The reaction solvent is water, methanol, n-propanol, isopropanol, n-butanol, isobutanol, t-butanol, 1,2-propandiol, 1,3-propandiol, 1,3-butandiol, or glycerol.
申请公布号 KR20120015021(A) 申请公布日期 2012.02.21
申请号 KR20100077209 申请日期 2010.08.11
申请人 AMOREPACIFIC CORPORATION 发明人 LEE, CHAN WOO;YOO, JAE WON;YUN, YU NA;KIM, SEO YOUNG;LEE, JIN YOUNG;KIM, JUN OH;CHO, JUN CHEOL
分类号 C07D407/12;A61K31/351;A61P17/10 主分类号 C07D407/12
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