发明名称 |
Method for preparation of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphtoic acid |
摘要 |
A method for preparation of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid is disclosed based on “one pot” synthesis approach including a direct synthesis of boronic acid derivative from 2-(1-adamantyl)-4-bromoanisole and cycloboranes with a subsequent Suzuki-Miyaura coupling with 6-halonaphtenoates and basic hydrolysis of the reaction product in ethylene glycol or 1,2-propanediol. |
申请公布号 |
US8119835(B2) |
申请公布日期 |
2012.02.21 |
申请号 |
US20070448672 |
申请日期 |
2007.12.28 |
申请人 |
KALVINSH IVARS;CHERNOBROVIJS ALEKSANDRS;TRIBULOVICH VYACHESLAV;LABEISH VLADIMIR;JSC GRINDEKS |
发明人 |
KALVINSH IVARS;CHERNOBROVIJS ALEKSANDRS;TRIBULOVICH VYACHESLAV;LABEISH VLADIMIR |
分类号 |
C07C63/34;C07C69/76 |
主分类号 |
C07C63/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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