发明名称 |
A METHOD FOR PRODUCING CERVICAL CANCER VACCINE USING BACILLUS SUBTILIS |
摘要 |
PURPOSE: A method for manufacturing a vaccine for cervical cancer using Bacillus subtilis is provided to ensure safety without toxicity. CONSTITUTION: A vaccine for preventing cervical cancer contains Bacillus subtilis transformed by a recombinant vector containing a gene encoding capsid proteins of human papillomavirus, or human paillomavirus-like virus particles. The vaccine is used by oral administration. A method for preparing the human paillomavirus-like virus particles comprises: a step of culturing the transformed Bacillus subtilis; and a step of collecting the particles. The capsid protein is L1 protein or L2 protein.
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申请公布号 |
KR20120014885(A) |
申请公布日期 |
2012.02.20 |
申请号 |
KR20110079769 |
申请日期 |
2011.08.10 |
申请人 |
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY |
发明人 |
KIM, CHUL HO;BAEK, JIN OH;SEO, JEONG WOO;KWON, OH SUK |
分类号 |
A61K39/12;A61K36/06;A61P35/00;C12N1/20 |
主分类号 |
A61K39/12 |
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