发明名称 |
THERAPEUTIC AGENT FOR GLAUCOMA COMPRISING Rho KINASE INHIBITOR AND PROSTAGLANDIN |
摘要 |
A therapeutic composition for treating glaucoma or for reducing intraocular pressure containing a combination of pharmaceutically effective amounts of drugs including (i) a Rho kinase inhibitor selected from the group consisting of (R)-(+)-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)-4-(1-aminoethyl)benzamide and 1-(5-isoquinolinesulfonyl)-homopiperazine, or a salt thereof and (ii) a prostaglandin which is latanoprost or a salt of latanoprost, and (iii) optionally a pharmaceutically acceptable carrier. A therapeutic composition for treating glaucoma or for reducing intraocular pressure containing a combination of pharmaceutically effective amounts of drugs comprising (i) a Rho kinase which is (R)-(+)-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)-4-(1-aminoethyl)benzamide or a slat thereof and (ii) a prostaglandin which is isopropyl unoprostone or a salt thereof, and (iii) optionally a pharmaceutically acceptable carrier.
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申请公布号 |
US2012040994(A1) |
申请公布日期 |
2012.02.16 |
申请号 |
US201113280684 |
申请日期 |
2011.10.25 |
申请人 |
NAKAJIMA TADASHI;MATSUGI TAKESHI;HARA HIDEAKI;SANTEN PHARMACEUTICAL CO., LTD. |
发明人 |
NAKAJIMA TADASHI;MATSUGI TAKESHI;HARA HIDEAKI |
分类号 |
A61K31/497;A61K31/437;A61K31/4409;A61K31/4725;A61K31/5377;A61K31/553;A61K31/5575;A61K45/06;A61P27/06;A61P43/00 |
主分类号 |
A61K31/497 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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