The invention relates to a chimeric monomer-dimer hybrid protein wherein said protein comprises a first and a second polypeptide chain, said first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and said second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.
申请公布号
AU2012200470(A1)
申请公布日期
2012.02.16
申请号
AU20120200470
申请日期
2012.01.27
申请人
SYNTONIX PHARMACEUTICALS, INC.
发明人
PETERS, ROBERT T.;MEZO, ADAM R.;RIVERA, DANIEL S.;BITONTI, ALAN J.;STATTEL, JAMES M.;LOW, SUSAN C.