发明名称 |
AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS |
摘要 |
There is provided compounds of formula (I), wherein Ra, Rb, R2 and R3 have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. a PI3-K and/or Flt3, and, optionally, a PIM family kinase) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease. |
申请公布号 |
WO2012020215(A1) |
申请公布日期 |
2012.02.16 |
申请号 |
WO2011GB01187 |
申请日期 |
2011.08.09 |
申请人 |
CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO);PASTOR FERNANDEZ, JOAQUIN;KURZ, GUIDO;RICO FERREIRA, MARIA DEL ROSARIO;SOILAN RODRIGUEZ, DAVID;ORTEGA SORET, MIGUEL ANGEL;LINK, WOLFANG;RABAL GRACIA, OBDULIA |
发明人 |
PASTOR FERNANDEZ, JOAQUIN;KURZ, GUIDO;RICO FERREIRA, MARIA DEL ROSARIO;SOILAN RODRIGUEZ, DAVID;ORTEGA SORET, MIGUEL ANGEL;LINK, WOLFANG;RABAL GRACIA, OBDULIA |
分类号 |
C07D513/04;A61K31/433;A61K31/4439;A61K31/454;A61K31/4545;A61K31/496;A61K31/4985;A61K31/513;A61K31/5377;A61P3/00;A61P5/00;A61P9/00;A61P35/00;A61P35/02;C07D519/00 |
主分类号 |
C07D513/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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