发明名称 AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS
摘要 There is provided compounds of formula (I), wherein Ra, Rb, R2 and R3 have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. a PI3-K and/or Flt3, and, optionally, a PIM family kinase) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease.
申请公布号 WO2012020215(A1) 申请公布日期 2012.02.16
申请号 WO2011GB01187 申请日期 2011.08.09
申请人 CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO);PASTOR FERNANDEZ, JOAQUIN;KURZ, GUIDO;RICO FERREIRA, MARIA DEL ROSARIO;SOILAN RODRIGUEZ, DAVID;ORTEGA SORET, MIGUEL ANGEL;LINK, WOLFANG;RABAL GRACIA, OBDULIA 发明人 PASTOR FERNANDEZ, JOAQUIN;KURZ, GUIDO;RICO FERREIRA, MARIA DEL ROSARIO;SOILAN RODRIGUEZ, DAVID;ORTEGA SORET, MIGUEL ANGEL;LINK, WOLFANG;RABAL GRACIA, OBDULIA
分类号 C07D513/04;A61K31/433;A61K31/4439;A61K31/454;A61K31/4545;A61K31/496;A61K31/4985;A61K31/513;A61K31/5377;A61P3/00;A61P5/00;A61P9/00;A61P35/00;A61P35/02;C07D519/00 主分类号 C07D513/04
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