| 发明名称 |
FRAGMENTATION RESISTANT IgG1 Fc-CONJUGATES |
| 摘要 |
The present invention provides compositions and methods relating to human IgG1 and IgG3 Fc-conjugates which are resistant to free-radical mediated fragmentation and aggregation. The present invention also provides compositions and methods for making the Fc-conjugates of the invention. |
| 申请公布号 |
US2012039880(A1) |
申请公布日期 |
2012.02.16 |
| 申请号 |
US201013265833 |
申请日期 |
2010.04.21 |
| 申请人 |
YAN BOXU;HU ZHONGHUA;KLEEMAN GERD RICHARD;YATES ZACHARY ADAM;ZHOU HONGXING;AMGEN INC. |
发明人 |
YAN BOXU;HU ZHONGHUA;KLEEMAN GERD RICHARD;YATES ZACHARY ADAM;ZHOU HONGXING |
| 分类号 |
A61K39/395;A61P43/00;C07H21/00;C07K16/00;C12N5/10;C12N15/63;C12P21/00 |
主分类号 |
A61K39/395 |
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