发明名称 |
SYSTEM AND METHOD FOR REVERTING ANTIBIOTIC TOLERANCE OF BACTERIAL PERSISTER CELLS |
摘要 |
A system and method for reverting the antibiotic tolerance of persister cells. Brominated furanones, which are quorum sensing inhibitors, are used to revert the antibiotic tolerance of persister cells and enhance their susceptibility to antibiotics by up to one hundred fold. Brominated furanones can be used against bacterial persister cells in biofilms or planktonic form. |
申请公布号 |
WO2012021514(A2) |
申请公布日期 |
2012.02.16 |
申请号 |
WO2011US47080 |
申请日期 |
2011.08.09 |
申请人 |
SYRACUSE UNIVERSITY;REN, DACHENG;PAN, JIACHUAN |
发明人 |
REN, DACHENG;PAN, JIACHUAN |
分类号 |
C12N1/38;A61P31/00;C12N1/20 |
主分类号 |
C12N1/38 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|