发明名称 Fused aminodihydropyrimidone derivatives
摘要 <p>A compound represented by the general formula (I) or a pharmaceutically acceptable salt thereof or a solvate thereof, wherein Ring A is a C aryl group or the like, L is -NRCO- or the like (wherein R is a hydrogen atom or the like), Ring B is a C aryl group or the like, X is a C alkylene group or the like, Y is a single bond or the like, Z is a C alkylene group or the like, R, R and R are each independently a hydrogen atom or the like, and R, R, R and R are independently a hydrogen atom, a halogen atom or the like, has an Aβproduction inhibitory effect or a BACE1 inhibitory effect and is useful as a prophylactic or therapeutic agent for a neurodegenerative disease caused by Aβand typified by Alzheimer-type dementia.</p>
申请公布号 AU2010275196(A1) 申请公布日期 2012.02.16
申请号 AU20100275196 申请日期 2010.07.21
申请人 EISAI R&D MANAGEMENT CO., LTD 发明人 CASTRO PINEIRO, JOSE LUIS;HALL, ADRIAN;MADIN, ANDREW;VO, NGOC-TRI
分类号 C07D491/048;A61K31/522;A61P25/28 主分类号 C07D491/048
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