摘要 |
<P>PROBLEM TO BE SOLVED: To predict and control changes in the state of a living body. <P>SOLUTION: The amount of expression of molecules in a living body is measured at a specified time interval, measured time-series data are divided into a periodic component, an environmental stimulus response component and a baseline component, the constant region of the time-series data is identified from variations in the baseline component or from the amplitude or periodic variations of the periodic component, and causal relationships between the identified constant regions are identified further. The relationship between variations in an internal environment and an external environment is identified, and from the identified causal relationships between the constant regions, changes in the state of the living body are inferred. Further, from the identified relationship between variations in the internal environment and the external environment, disease onset in the living body can be inferred. The molecules can be molecules in the blood or molecules in a culture medium. <P>COPYRIGHT: (C)2012,JPO&INPIT |