发明名称 LUMEN FORMATION INHIBITOR OF ENDOTHELIAL CELL
摘要 <P>PROBLEM TO BE SOLVED: To provide a lumen formation inhibitor which is characterized by not substantially inhibiting the growth of an endothelial cell with a deoxy sugar derivative or a sugar alcohol derivative as an effective component. <P>SOLUTION: There is provided the lumen forming inhibitor which is characterized in that it does not substantially inhibit the growth of the endothelial cell with the deoxy sugar derivative or the sugar alcohol derivative except for 1, 5-Anhydro-2-deoxy-D-arabino-hexitol (ADAH, formula (4)) as the effective component. Particularly, D-Glucal (formula (1)) as the sugar alcohol derivative, or 2, 3-Dideoxy-D-erythro-hexose(DEH, formula (2)) as the deoxy sugar derivative, or Alkyl 2, 3-dideoxy-D-erythro-hexapyranoside (ADEH, formula (5)) is used as the effective component. (In the formula (5), R denotes a 1-5C alkyl group). <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012031108(A) 申请公布日期 2012.02.16
申请号 JP20100172767 申请日期 2010.07.30
申请人 KAGAWA UNIV;NOGUCHI INSTITUTE 发明人 TSUKAMOTO IKUKO;KONISHI RYOJI;KUBOTA YASUO;OSUMI KENJI;MIZUNO MASAMORI
分类号 A61K31/351;A61K31/7004;A61K31/7028;A61P3/10;A61P17/06;A61P19/02;A61P27/02;A61P29/00;A61P35/00;A61P43/00;C07D309/30;C07H3/08;C07H15/04 主分类号 A61K31/351
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