A COMPREHENSIVE METHYLOME MAP OF MYELOID AND LYMPHOID COMMITMENT FROM HEMATOPOIETIC PROGENITORS
摘要
Provided herein are differentially methylated regions (DMRs) of multipotent progenitor cells (MPPs) and oligopotent progenitor cells and methods of use thereof. The invention provides methods for detecting and analyzing alterations in the methylation status of DMRs in such progenitor cells as well as methods for differentiating such cells.
申请公布号
WO2012021867(A2)
申请公布日期
2012.02.16
申请号
WO2011US47681
申请日期
2011.08.12
申请人
THE JOHNS HOPKINS UNIVERSITY;THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;FEINBERG, ANDREW, P.;WEISSMAN, IRVING, L.