MIKROFLUIDVORRICHTUNG MIT VARIABLEM VOLUMENMATERIAL

摘要

The microfluidic device (110) to produce a reactional mixture of two different liquids, comprises a first plate (112) forming a substrate and having perforations, activable materials (114, 116) for delimiting channel portions arranged on either side of the first plate in several locations, a second plate forming a substrate and having perforations staggered with respect to perforations of the first plate, a third plate forming a substrate and having perforations staggered with respect to the perforations of the second plate, and an anti-adhesive layer. The microfluidic device (110) to produce a reactional mixture of two different liquids, comprises a first plate (112) forming the substrate and having perforation, activable materials (114, 116) for delimiting channel portions arranged on either side of the first plate in several locations, a second plate forming substrate and having perforations staggered with respect to perforations of the first plate, a third plate forming substrate and having perforations staggered with respect to the perforations of the second plate, and an anti-adhesive layer between the first plate and the activable material. The material is capable of varying its volume by activation, and is arranged at the locations based on an arrangement, which enables its transformation from a first configuration into a second configuration. A three-dimensional network (10) is modified in the second configuration according to the selected locations that are activated in a first phase and to different paths of the liquid having channel portions parallel to a plane of the first plate. The activable material disposed between the first plate and the second plate has a passage located in an extension of one of perforations of the first plate so that the activation of the activable material locations allows the creation of channels, which make the connection of liquid between the perforation of the first plate and the second plate. During the first phase, the transformation from the first to second configuration and the modification of three-dimensional network corresponds to a creation of channels between activated locations. The channels form the three-dimensional network with the perforations. In a second phase, the activation of other locations of activable material is located between the first plate and second plate for allowing a closing of channels to prevent the connection of fluid between the perforation of the second plate and the first plate. The activable material is composed of a layer covering the first plate, and is activated by heat, chemical or electromagnetic stimulation. A volume of the activable material is increased when the material is activated.