发明名称 |
CANCER ANTIGEN MAGE-A9 AND USES THEREOF |
摘要 |
<p>The present invention relates to the detection of MAGE-A9 in a biological sample and to the diagnosis, prevention and treatment of MAGE-A9-associated aberrant cell growth, through the targeting of the MAGE-A9 polypeptide and/or polynucleotide. Diagnosis is accomplished by examining or monitoring cells for perturbations in MAGE-A9 expression. Prevention and treatment are accomplished by administering to a subject MAGE-A9 as a protein or a fragment thereof or under form of a DNA expression vector, as well as by administering to a subject a MAGE-A9 gene product-binding agent. Compositions and commercial kits are also provided.</p> |
申请公布号 |
EP1951891(B1) |
申请公布日期 |
2012.02.15 |
申请号 |
EP20060817649 |
申请日期 |
2006.11.14 |
申请人 |
UNIVERSITE LAVAL |
发明人 |
BERGERON, ALAIN;PICARD, VALERIE;LARUE, HELENE;FRADET, YVES |
分类号 |
C12P21/08;A61K31/7088;A61K39/00;A61K39/395;A61K48/00;A61P35/00;C07K16/18;C12N5/12;C12Q1/02;C12Q1/68;G01N33/53;G01N33/574 |
主分类号 |
C12P21/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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