| 摘要 |
The method of obtaining enantiomerically enriched condensation products consists of subjecting a racemic acid or an acid of low enantiomeric purity to the action of a condensing reagent - a chiral N-triazinylammonium tetrafluoroborate (formula 1), a chiral N-triazinylammonium bistetrafluoroborate (formula 2), a chiral N-triazinylammoniumoligotetrafluoroborate (formula 3), a favourably chiral tetrafluoroborate (formula 1), or chiral bistetrafluoroborate (formula 2), where X, Y signify mutually independently substituents: alkoxy substituent; alkoxy, aryloxy substituent; aryloxy, heteroaryloxy, alkylamine substituent; alkylamine, dialkylamine substituent; alkylamine substituent; dialkylamine, arylamine substituent; arylamine or a heterocyclic group substituent; NR 1 R 2 R 3 substituent means a fragment derived from a chiral tertiary amine, where R 1 , R 2 , R 3 signify mutually independently substituted or non-substituted alkyl, cycloalkyl, bicycloalkyl, heterocyclic, aryl, heteroaryl group; N 1 R 2 R 3 -R 4 R 5 R 6 substituent means a fragment derived from a chiral tertiary diamine, where R 1 R 2 R 3 R 4 R 5 R 6 signify mutually independent substituted or non-substituted alkyl, cycloalkyl, bicycloalkyl, heterocyclic, aryl, heteroaryl group, and n refers to the degree of oligomerization and n‰¥2, in an organic solvent, which is favourable at a lowered temperature, and then subject to a nucleophilic component.
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