发明名称 Macrolide antibiotics and their use for medical purposes
摘要 The invention provides novel Thuggacin-Type macrolide compounds which form rearrangement products forming a lacton bond to different carbon atoms. The novel compounds can be produced by fermentation of Sorangium cellulosum and Chondromyces crocatus and can be isolated by adsorption and chromoatograhic processing steps. The compounds are found to have antibiotic activity. The invention also relates to Thuggacin A, Thuggacin B, Thuggacin C, 13-Methyl-Thuggacin A, Thuggacin CMC-A, Thuggacin CMC-B and Thuggacin CMC-C AS Antimycobacterial Agents.
申请公布号 US8114864(B2) 申请公布日期 2012.02.14
申请号 US20070515695 申请日期 2007.11.09
申请人 JANSEN ROLF;KUNZE BRIGITTE;IRSCHIK HERBERT;HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG 发明人 JANSEN ROLF;KUNZE BRIGITTE;IRSCHIK HERBERT
分类号 A61K31/395;C07D487/04 主分类号 A61K31/395
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