发明名称 |
Oral pharmaceutical dosage forms comprising a proton pump inhibitor and a NSAID |
摘要 |
An oral pharmaceutical dosage form comprising an acid susceptible proton pump inhibitor and one or more NSAIDs in a fixed formulation, wherein the proton pump inhibitor is protected by an enteric coating layer. The fixed formulation is in the form of an enteric coating layered tablet, a capsule or a multiple unit tableted dosage form. The multiple unit dosage forms are most preferred. The new fixed formulation is especially useful in the treatment of gastrointestinal side-effects associated with NSAID treatment. |
申请公布号 |
US8114435(B2) |
申请公布日期 |
2012.02.14 |
申请号 |
US20090368076 |
申请日期 |
2009.02.09 |
申请人 |
DEPUI HELENE;LUNDBERG PER;ASTRAZENECA AB |
发明人 |
DEPUI HELENE;LUNDBERG PER |
分类号 |
A61K9/48;C07D401/12;A61K9/20;A61K9/24;A61K9/26;A61K9/28;A61K9/36;A61K9/50;A61K9/52;A61K9/54;A61K31/19;A61K31/4184;A61K31/44;A61K31/4427;A61K45/06;A61P31/04 |
主分类号 |
A61K9/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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