发明名称 |
SYNTHESIS OF ACYL-PANTETHEINE DERIVATIVES AND THE USE THEREOF IN THE SYNTHESIS OF ACYL-COENZYME A DERIVATIVES |
摘要 |
The present invention relates to a novel synthesis method for acyl-pantetheine derivatives. The present invention further relates to the use of said synthesized acyl-pantetheine derivatives as a starting material in the enzymatic synthesis of acyl-coenzyme A derivatives. According to a first aspect thereof, the present invention provides a method for the synthesis of acyl-pantetheine derivatives, the method including the steps of: a) providing a source of pantetheine; b) providing a source of acyl ester; and c) contacting the source of pantetheine with the source of acyl ester to form the corresponding acyl-pantetheine derivative, having the general formula (I), wherein R is an acyl group.The present invention also provides a method for the synthesis of acyl-coenzyme A derivatives as well as the use of a source of pantetheine and a source of acyl ester in the preparation steps of these two methods. |
申请公布号 |
WO2012017400(A1) |
申请公布日期 |
2012.02.09 |
申请号 |
WO2011IB53458 |
申请日期 |
2011.08.03 |
申请人 |
NORTH-WEST UNIVERSITY;VAN DIJK, ALBERDINA AIKE;BADENHORST, CHRISTOFFEL PETRUS STEPHANUS |
发明人 |
VAN DIJK, ALBERDINA AIKE;BADENHORST, CHRISTOFFEL PETRUS STEPHANUS |
分类号 |
C07C327/00;C07H19/20 |
主分类号 |
C07C327/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|