发明名称 |
METHODS AND COMPOSITIONS FOR THE INHIBITION OF FRUCTOKINASE |
摘要 |
The invention relates to the use of isoform-specific fructokinase (ketohexokinase) (KHK) inhibitors alone or in combination with various agents to both prevent and treat a wide variety of diseases including, but not limited to, sugar craving, obesity, features of metabolic syndrome (including insulin resistance, hypertriglyceridemia, hypertension, and fatty liver), polyuria, proximal tubular injury, and diabetic kidney disease. |
申请公布号 |
WO2012019188(A2) |
申请公布日期 |
2012.02.09 |
申请号 |
WO2011US46938 |
申请日期 |
2011.08.08 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODYCORPORATE;JOHNSON, RICHARD, J.;LANASPA, MIGUEL, A.;ISHIMOTO, TAKUJI |
发明人 |
JOHNSON, RICHARD, J.;LANASPA, MIGUEL, A.;ISHIMOTO, TAKUJI |
分类号 |
A61K39/395;A61K31/70;A61K31/7105;A61K48/00;A61P3/00;A61P3/04;A61P3/10 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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