发明名称 A CRYSTALLINE FORM OF (S)-PYRROLIDINE-1,2-DICARBOXYLIC ACID 2-AMIDE 1-(4 -METHYL-5-[2-(2,2,2-TRIFLUORO-1,1-DIMETHYL-ETHYL)-PYRIDIN-4-YL]-THIAZOL-2-YL)-AMIDE AND ITS USE AS PI3K INHIBITOR
摘要 <p>The present invention relates to specific solid forms of (S)-pyrrolidine-l,2-dicarboxylic acid 2-amide l-(4-methyI-5-[2-(2,2,2-trifluoro-l,l-dimethyl-ethyl)-pyridin-4-yl]-thiazol-2-yl)-amide, (I), and its hydrates and solvates. The present invention further relates to processes for preparing said solid forms, pharmaceutical compositions comprising said solid forms, and methods of using said solid forms and pharmaceutical compositions to treat disease.</p>
申请公布号 WO2012016970(A1) 申请公布日期 2012.02.09
申请号 WO2011EP63256 申请日期 2011.08.01
申请人 NOVARTIS AG;GALLOU, ISABELLE SYLVIE;GAUER, CORNELIUS;STOWASSER, FRANK 发明人 GALLOU, ISABELLE SYLVIE;GAUER, CORNELIUS;STOWASSER, FRANK
分类号 C07D417/14;A61K31/4439;A61P35/00 主分类号 C07D417/14
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