| 摘要 |
<P>PROBLEM TO BE SOLVED: To develop a biomarker which enables objective and simple diagnosis and assessment of fatigue, and a diagnostic technology using the biomarker. <P>SOLUTION: The ratio of measurement values of glucose, citric acid and cis-aconitic acid in a biological sample of a subject to the measurement values of healthy subjects is calculated, and the glucose ratio, citric acid ratio, and cis-aconitic acid ratio are used to assess and/or determine the fatigue. In the same way, the isocitric acid ratio is calculated, combined with the three ratios, and used to assess and/or determine the fatigue. <P>COPYRIGHT: (C)2012,JPO&INPIT |
