发明名称 |
COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS |
摘要 |
We have discovered that p63 inhibition results in increased cellular proliferation. We have also performed a screen for agents capable of increasing cellular proliferation, (e.g., of stem cells such as skin-derived precursors (SKPs)). The invention therefore invention provides compositions, methods, and kits for increasing proliferation of cells, using compounds that decrease p63 expression or activity or using the compounds described herein. The invention also features methods of using these compounds for increasing hair growth, improving skin health, or promoting skin repair in a subject. |
申请公布号 |
WO2012018643(A2) |
申请公布日期 |
2012.02.09 |
申请号 |
WO2011US45416 |
申请日期 |
2011.07.26 |
申请人 |
THE HOSPITAL FOR SICK CHILDREN;MILLER, FREDA;KAPLAN, DAVID;SMITH, KRISTEN;PARIS, MARYLINE;NASKA, SIBEL |
发明人 |
MILLER, FREDA;KAPLAN, DAVID;SMITH, KRISTEN;PARIS, MARYLINE;NASKA, SIBEL |
分类号 |
A61K31/7028;A61K31/09;A61K31/14;A61K31/155;A61K31/352;A61K31/357;A61K31/366;A61K31/382;A61K31/40;A61K31/4168;A61K31/4355;A61K31/4745;A61K31/498;A61K31/522;A61K31/5375;A61K31/5575;A61K31/57;A61K31/675;A61K31/7034;A61P17/00;A61P17/02;C12N5/071;C12N5/09;C12Q1/02 |
主分类号 |
A61K31/7028 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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