发明名称 S1P Receptors Modulators
摘要 The invention relates to novel compounds that have S1P receptor modulating activity and, preferably, apoptotic activity and/or anti proliferative activity against cancer cells and other cell types. Further, the invention relates to a pharmaceutical comprising at least one compound of the invention for the treatment of diseases and/or conditions caused by or associated with in-appropriate S1P receptor modulating activity or expression, for example, cancer. A further aspect of the invention relates to the use of a pharmaceutical comprising at least one compound of the invention for the manufacture of a medicament for the treatment of diseases and/or conditions caused by or associated with inappropriate S1P receptor modulating activity or expression such as cancer.
申请公布号 US2012034270(A1) 申请公布日期 2012.02.09
申请号 US200913124543 申请日期 2009.10.16
申请人 GROBELNY DAMIAN W.;GILL GURMIT S.;AKAAL PHARMA PTY LTD 发明人 GROBELNY DAMIAN W.;GILL GURMIT S.
分类号 A61K31/136;A61K31/137;A61K31/18;A61K31/343;A61K31/4035;A61K31/404;A61K31/4045;A61K31/4245;A61K31/47;A61K31/472;A61K31/4725;A61K31/55;A61P1/16;A61P7/00;A61P9/00;A61P11/00;A61P29/00;A61P31/00;A61P35/00;A61P37/02;A61P37/06;C07C215/68;C07C225/16;C07C311/37;C07D209/08;C07D209/12;C07D209/38;C07D209/44;C07D215/06;C07D217/04;C07D223/16;C07D307/81;C07D405/12;C07D413/10 主分类号 A61K31/136
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