| 发明名称 |
CONSERVED HBV AND HCV SEQUENCES USEFUL FOR GENE SILENCING |
| 摘要 |
Conserved consensus sequences from known hepatitis B virus strains and known hepatitis C virus strains, which are useful in inhibiting the expression of the viruses in mammalian cells, are provided. These sequences are useful to silence the genes of HBV and HCV, thereby providing therapeutic utility against HBV and HCV viral infection in humans. |
| 申请公布号 |
US2012035240(A1) |
申请公布日期 |
2012.02.09 |
| 申请号 |
US200513065601 |
申请日期 |
2005.12.12 |
| 申请人 |
PACHUK CATHERINE J.;SATISHCHANDRAN CHANDRASEKHAR;ZURAWSKI, JR. VINCENT R.;MINTZ LIAT;ALNYLAM PHARMACEUTICALS, INC. |
发明人 |
PACHUK CATHERINE J.;SATISHCHANDRAN CHANDRASEKHAR;ZURAWSKI, JR. VINCENT R.;MINTZ LIAT |
| 分类号 |
A61K31/713;A61P31/14;A61P31/20;C07H21/02;C07H21/04;C12N5/071;C12N5/10;C12N15/113;C12N15/63;C12N15/85 |
主分类号 |
A61K31/713 |
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