Photosensitive cardiac rhythm modulation structures and systems are described. A genetically-engineered tissue comprising a population of pacing cells expressing a photosensitive membrane transport mechanism that is responsive to light of a particular wavelength(s) combined with one or more of a light source, a power generator, and a sensor provides pacemaker and/or defibrillator function to a subject. The systems further provide in vitro model systems for electrophysiological studies.
申请公布号
WO2012006320(A8)
申请公布日期
2012.02.09
申请号
WO2011US43027
申请日期
2011.07.06
申请人
PRESIDENT AND FELLOWS OF HARVARD COLLEGE;PARKER, KEVIN, KIT;BRIGHAM, MARK, D.