发明名称 |
4'-SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF HCV RNA REPLICATION |
摘要 |
The present invention relates to the use of nucleoside derivatives of formula I wherein B signifies a 9-purinyl residue B1 of formula or a 1-pyrimidyl residue B2 of formula wherein the symbols are as defined in the specification, and of pharmaceutically acceptable salts thereof; for the treatment of diseases mediated by the Hepatitis C Virus (HCV), for the preparation of a medicament for such treatment and to pharmaceutical compositions containing such compounds.
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申请公布号 |
US2012034184(A1) |
申请公布日期 |
2012.02.09 |
申请号 |
US201113274743 |
申请日期 |
2011.10.17 |
申请人 |
DEVOS RENE ROBERT;HOBBS CHRISTOPHER JOHN;JIANG WEN RONG;MARTIN JOSEPH ARMSTRONG;MERRETT JOHN HERBERT;NAJERA ISABEL;SHIMMA NOBUO;TSUKUDA TAKUO |
发明人 |
DEVOS RENE ROBERT;HOBBS CHRISTOPHER JOHN;JIANG WEN RONG;MARTIN JOSEPH ARMSTRONG;MERRETT JOHN HERBERT;NAJERA ISABEL;SHIMMA NOBUO;TSUKUDA TAKUO |
分类号 |
A61K31/7068;C07H19/067;A61K31/52;A61K31/7072;A61K31/7076;A61K31/708;A61K38/19;A61K38/20;A61K38/21;A61K45/06;A61P1/16;A61P29/00;A61P31/14;A61P37/02;C07H19/04;C07H19/06;C07H19/073;C07H19/167;C07H19/173 |
主分类号 |
A61K31/7068 |
代理机构 |
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代理人 |
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地址 |
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