发明名称 |
ON-DEMAND AND REVERSIBLE DRUG RELEASE BY EXTERNAL CUE |
摘要 |
The invention provides a method to release drugs from a polymer matrix upon demand without degrading the matrix. By applying ultrasound to a self-healable polymer matrix in physiological environment, compounds of both low-molecular and high-molecular weights encapsulated in the matrix are delivered at controlled rates, while the integrity and stiffness of the matrix are unaffected.
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申请公布号 |
US2012035531(A1) |
申请公布日期 |
2012.02.09 |
申请号 |
US201013147870 |
申请日期 |
2010.02.01 |
申请人 |
ZHAO XUANHE;HUEBSCH NATHANIEL D.;MOONEY DAVID J.;SUO ZHIGANG;PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
ZHAO XUANHE;HUEBSCH NATHANIEL D.;MOONEY DAVID J.;SUO ZHIGANG |
分类号 |
A61M37/00 |
主分类号 |
A61M37/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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