| 发明名称 |
PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING |
| 摘要 |
The invention provides novel inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula I: wherein A, X, Y R1, R2, R3, R4, m and n are as described herein. |
| 申请公布号 |
PT1789390(E) |
申请公布日期 |
2012.02.08 |
| 申请号 |
PT20050795325T |
申请日期 |
2005.09.02 |
| 申请人 |
GENENTECH, INC.;CURIS, INC. |
发明人 |
LIANG BAO;GEORGETTE CASTANEDO;JANET GUNZNER;DANIEL SUTHERLIN;MARK STANLEY;REBECCA LALONDE;SHUMEI WANG;MARK REYNOLDS;SCOTT SAVAGE;KIMBERLY MALESKY;MICHAEL DINA;MICHAEL F. T. KOEHLER |
| 分类号 |
C07D213/40;A61K31/4418;A61K31/4427;A61P35/00;C07D213/38;C07D213/56;C07D213/70;C07D213/75;C07D213/81;C07D213/82;C07D401/12;C07D401/14;C07D405/12;C07D409/12;C07D413/12;C07D417/04;C07D417/12;C07F9/142 |
主分类号 |
C07D213/40 |
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